@strodown
It's a fresh install. I don't update.
I add this lines to retroarch-core-options.cfg file:
beetle_psx_hw_cd_fastload = "12x"
beetle_psx_hw_cd_access_method = "async"
beetle_psx_hw_internal_resolution = "4x"
Then I started the game, but the settings were not applied. If I reopen retroarch-core-options.cfg file, it looks as if I haven't edited it.