Fixed !
here is the correct code to mount (according that my ISO is in a directory called "source_cd", and need to be call "source~1" in DOS mode :
imgmount D "C:\source~1\scream.cue" -t iso -fs iso
Then, you have to call "install" (from d:) to install the game, then "setup" (from c:) to configure it, and finaly launch the game with "S2" (from c:) ... and lets play (after few try, I get it working, can't understand why it doesn't on the first one) !