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@nordicpower try activating the Joypad to Keyboard option in Retroarch‘s menu (arrow) and pressing SELECT on your gamepad to simulate the ESC key press.
http://docs.libretro.com/library/neko_project_ii_kai/#controllers
@Tornelf regarde dans retroarch si il y a l option Disk Swap Interface et teste à partir de là Pas eu le temps de tester.