Out of curiousity, did you change any information about the n64 in the es_systems.cfg?

The n64 emulator didn't run my zipped roms, so if your rom was zipped it could of been the issue.

Is the rom zip or unzipped?

It's come to my attention that there's a specific method to being able to add new emulators or games. I've been curious about this because i like my wswan and wswancolor to be in separate folders but i couldn't find the proper method of directing the emulators to launch the roms/games. I'm aware on how to add them to the emulationstation but unable to figure out how to get the rest to work.   Solved: Some emulators needed to be added to the emulatorlauncher.pyc